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Welcome to CONNECT-TBI


CONNECT-TBI is a unique, international, multi-center, multi-investigator project. Our goal is to support researchers investigating the pathology of traumatic brain injury (TBI) and its outcomes, including TBI related neurodegeneration (TReND).

As a ‘Center Without Walls’, CONNECT-TBI brings together a network of expert neuropathologists, clinicians and academics across 13 leading institutions to:

  • coordinate existing research tissue archives and standardize procedures for new tissue donations
  • streamline access to these resources and make them available for global research

Established in 2019, CONNECT-TBI is funded by the National Institute of Neurological Disorders and Stroke (NINDS) and the National Institute on Aging (NIA).

We are confident that CONNECT-TBI will transform global research and accelerate our understanding of acute TBI and the association between TBI and neurodegenerative disease, including Alzheimer’s disease and Alzheimer’s disease related disorders (AD/ADRD).

Douglas H. Smith and William Stewart
University of Pennsylvania and
University of Glasgow

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